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Drug Info for oxervate

Ophthalmic cenegermin-bkbj is used to treat neurotrophic keratitis (a degenerative eye disease that can lead to damage of the cornea [the outermost layer of the eye]). Cenegermin-bkbj is in a class of medications called recombinant human nerve growth factors. It works to heal the cornea.

  • Into the eye

Ophthalmic routeWash your hands with soap and water before and after using this medicine.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Gently push the plunger down until at least a drop is released into the eye pocket. Do not touch your eye with the tip of the pipette. With your head still tilted back, blink a few times so that the medicine covers the surface of your eye.

Your doctor will tell you how much medicine to use. Do not use more than directed.

Missed dose: If you miss a dose, take your next dose at your scheduled time. Do not take an extra dose to make up for a missed dose.

This medicine is available as a Delivery System Kit. Make sure to follow the instructions carefully.

If you wear contact lenses, remove them before using this medicine. You may insert them again after 15 minutes.

Store the unopened vial in its original carton in the refrigerator. Keep the opened vial in the refrigerator for up to 12 hours or at room temperature. Do not shake the vial. Throw away any unused medicine after 12 hours.

Use a new sterile disinfectant wipe and a new pipette each time.

To prepare the medicine:Push down the vial adapter blister pack onto the vial until it snaps into place over the vial's neck. Do not remove it from the vial after connecting it.Clean the surface of the valve on the connector part of the vial adapter with a sterile disinfectant wipe. Let it dry for about 1 minute.Screw a pipette (clockwise) into the connector part of the vial adapter. Make sure it is pushed all the way down.Turn the vial upside-down and gently pull the plunger until it stops to draw the eye drop solution into the pipette.Check the pipette to make sure it contains the eye drop solution. If it is empty, keep the vial with the connected pipette upside-down, push the plunger all the way in and pull it out again.Unscrew (counter-clockwise) and pull the pipette straight up after it has been correctly filled.

Ophthalmic routeLie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

Throw the used pipette right away after use, even if there is still medicine left in it.

This medicine is generally considered safe for most people. Talk to your doctor if you have concerns.

Tell your doctor if you are pregnant or breastfeeding, or if you have other eye or vision problems.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

This medicine may cause blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

Ophthalmic routeIf you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it.

If you are also using other eye medicines together with cenegermin-bkbj, use them at least 15 minutes from each other. Use cenegermin-bkbj 15 minutes before using any eye ointment, gel, or other viscous eye drops.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Feeling of having something in the eye
  • Blurred or decreased vision or any change in vision
  • Irritation, swelling, or tearing of the eye
  • Eye discomfort, eye pain