Neostigmine Methylsulfate

Neostigmine Methylsulfate is an anticholinesterase agent used to treat patients with myasthenia gravis when oral therapy cannot be used. It is also used for the prevention and treatment of postoperative distention and urinary retention after mechanical obstruction has been excluded. It works by increasing movement of the muscles in the body.

• Simplist Neostigmine Methylsulfate
• Bloxiverz
• Bloxiverz Novaplus
• PremierPro Rx Neostigmine Methylsulfate

• Bloxiverz
• Enlon
• Firdapse
• Guanidine HCl
• Mestinon
• Mytelase
• Neostigmine Methylsulfate
• Prostigmin
• pyRIDostigmine Bromide
• pyRIDostigmine Bromide ER
• Regonol
• Ruzurgi

• Injectable

• By injection

Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin, into a muscle, or into a vein.

Injection routeA nurse or other health provider will give you this medicine.

You should not receive this medicine if you have had an allergic reaction to neostigmine, or if you have an intestine or urinary blockage, or swelling of the lining of your abdomen.

Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney or liver disease, myasthenia gravis (severe muscle weakness), asthma, seizures, an overactive thyroid, or stomach problems.

This medicine may cause your heartbeat to slow. Tell your doctor if you have heart disease, heart rhythm problems, or low blood pressure. You may have a higher risk if you have these heart problems.

Lightheadedness or fainting

Twitching or muscle movements you cannot control, problems with balance or walking

Make sure your doctor knows if you are also taking medicine to treat or prevent an infection (such as kanamycin, neomycin, streptomycin), or medicine to treat a heart rhythm problem (such as amiodarone, disopyramide, dofetilide, flecainide, Cordarone®, Norpace®, Tambocor®, Tikosyn®).

This medicine may cause your heartbeat to slow. Tell your doctor if you have heart disease, heart rhythm problems, or low blood pressure. You may have a higher risk if you have these heart problems.

• Twitching or muscle movements you cannot control, problems with balance or walking
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Fast, slow, or uneven heartbeat
• Lightheadedness or fainting
• Nausea, vomiting, diarrhea, stomach pain
• Drooling, or more saliva than usual
• Pain, itching, burning, swelling, or a lump under your skin where the needle is placed