Invokamet Xr

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Invokamet Xr

Drug Info for invokamet xr

Canagliflozin is used along with diet and exercise, and sometimes with other medications, to lower blood sugar levels in people with type 2 diabetes (condition in which blood sugar is too high because the body does not produce or use insulin normally). Canagliflozin is also used to reduce the risk of stroke, heart attack, or death in people who have type 2 diabetes along with heart and blood vessel disease. Canagliflozin is also used to reduce the risk of end-stage kidney disease, worsening of kidney function, needing to be hospitalized for heart failure, and cardiovascular death in people who have type 2 diabetes along with severe kidney disease. Canagliflozin is in a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It lowers blood sugar by causing the kidneys to get rid of more glucose in the urine. Canagliflozin is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood). Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Invokamet XR contains canagliflozin and metformin and is used with proper diet and exercise to control high blood sugar in people with type 2 diabetes. It works by helping to restore your body's proper response to the insulin you naturally produce.

  • Invokamet
  • Invokamet XR

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Oral routeIt is best to take this medicine with food or milk.

Swallow the extended-release tablet whole. Do not crush, break, or chew it. Take it with the morning meal.

If you take the extended-release tablet, part of the tablet may pass into your stools. This is normal and is nothing to worry about.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Store the medicine in the original container to protect it from moisture. You may also store the tablets in a pill box or pill organizer for up to 30 days only. Store at room temperature, away from heat, moisture, and direct light.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to canagliflozin or metformin, or if you have diabetic ketoacidosis (high ketones and acid in the blood).

Tell your doctor if you are pregnant. Do not use this medicine during the second and third part of your pregnancy, unless your doctor tells you to. If you had problems ovulating or have irregular periods, this medicine may cause you to ovulate, which could lead to pregnancy if you are sexually active. Talk to your doctor about effective birth control while you are using this medicine.

Do not breastfeed during treatment with this medicine.

Tell your doctor if you have kidney disease, liver disease, heart disease, blood vessel disease, adrenal or pituitary gland disease, heart failure, vitamin B12 deficiency, nerve problems, type 1 diabetes, an infection, or a history of pancreas problems, genital yeast or urinary tract infections, leg surgery, or foot ulcers. Tell your doctor if you are on a low-salt diet, if you drink alcohol, or if you are having surgery or other procedures.

This medicine may cause the following problems:Lactic acidosis (too much acid in the blood)Increased risk for leg, toe, or midfoot amputation (removal)Low blood pressureKetoacidosis (high ketones and acid in the blood), which can be life-threateningKidney problemsLow blood sugar levels, when used with other diabetes medicinesIncreased risk of genital yeast or urinary tract infections (including pyelonephritis, urosepsis)Fournier's gangrene (skin or tissue damage of the area between the anus and genitals)Increased risk for broken bones

Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may interact with the dye used for an x-ray or a CT scan.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Some medicines can affect how canagliflozin/metformin works. Tell your doctor if you are using any of the following:Acetazolamide, cimetidine, digoxin, dichlorphenamide, dolutegravir, isoniazid, lithium, morphine, nicotinic acid, quinine, ranitidine, ranolazine, rifampin, ritonavir, trimethoprim, vandetanibBirth control pillsBlood pressure medicineDiuretic (water pill, including amiloride, triamterene)Insulin or other diabetes medicineMedicine for heart rhythm changes (including procainamide, quinidine)Medicine to treat seizures (including phenobarbital, phenytoin, topiramate, zonisamide)NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)Thyroid medicine

Several other medicines may affect your blood sugar levels. Closely monitor your blood sugar levels when you start or stop another medicine while you are using canagliflozin/metformin.

If you are taking an evening dose of metformin extended-release tablets, you should skip the last dose before starting treatment with this medicine the following morning.

Limit the amount of alcohol you drink. Heavy alcohol use increases your risk for lactic acidosis.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Lightheadedness, dizziness, fainting
  • Increased hunger, headache, confusion, shaking, trembling, sweating
  • Fast or trouble breathing, stomach pain, nausea, vomiting, severe weakness, tiredness
  • Pain, tenderness, redness, or swelling of the area between the anus and genitals, fever, unusual tiredness or weakness
  • Confusion, severe weakness, uneven heartbeat, numbness in your hands, feet, or lips
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, trouble urinating, painful or difficult urination, lower back or side pain, chills
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Pain, tenderness, sores or ulcers, or infections on the leg or foot
  • White or yellow vaginal discharge, vaginal itching or odor
  • Redness, itching, pain, or swelling of the penis, bad-smelling discharge from the penis
Frequently Asked Questions

On average, a supply of 30, 50 mg-1000 mg Invokamet XR oral tablets, extended release cost about $258 without insurance. Cost may vary depending on dosage, pharmacy location and insurance coverage. Lower your prescription cost when you use our free coupon card.

Invokamet XR coupon card can be used at any participating pharmacy nationwide including Walmart, Walgreen and CVS/pharmacy. Enter your zip code on the Invokamet XR page of our site to see which pharmacies near you accept our Invokamet XR discount card. Then use it to save on your next prescription.

Invokamet XR contains canagliflozin and metformin. There is currently no generic version of Invokamet XR available in the United States. An alternative brand name drug is Invokamet. Use our free prescription coupon card for savings on your prescription of Caziant or the alternative brand name.

You can save on Invokamet XR by using a coupon from the manufacturer’s website. Eligible patients can also save on Invokamet XR through Johnson & Johnson Patient Assistance Foundation, Inc. Hospital Access Patient Assistance Program and Johnson & Johnson Patient Assistance Foundation, Inc. Patient Assistance Program. Contact these programs directly for more information. In addition, you can save on your prescription of Invokamet XR by using our OptionRx coupon card. It is free and easy to use and customers typically save more by doing so.