Invokamet Xr

Invokamet XR contains canagliflozin and metformin and is used with proper diet and exercise to control high blood sugar in people with type 2 diabetes. It works by helping to restore your body's proper response to the insulin you naturally produce.

• Invokamet
• Invokamet XR

• Actoplus Met
• Actoplus met XR
• Alogliptin-metFORMIN HCl
• Alogliptin-Pioglitazone
• Appformin
• Appformin-D
• Avandamet
• Avandaryl
• D-Care DM2
• Dapagliflozin Pro-metFORMIN ER
• Duetact
• glipiZIDE-metFORMIN HCl
• Glucovance
• glyBURIDE-metFORMIN
• Glyxambi
• Invokamet
• Invokamet XR
• Janumet
• Janumet XR
• Jentadueto
• Jentadueto XR
• Juvisync
• Kazano
• Kombiglyze XR
• Oseni
• Pioglitazone HCl-Glimepiride
• Pioglitazone HCl-metFORMIN HCl
• PrandiMet
• Qtern
• Repaglinide-metFORMIN HCl
• sAXagliptin-metFORMIN ER
• Segluromet
• Soliqua
• Steglujan
• Synjardy
• Synjardy XR
• Trijardy XR
• Xigduo XR
• Xultophy

• Long Acting Tablet
• Tablet

• By mouth

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Oral routeIt is best to take this medicine with food or milk.

Swallow the extended-release tablet whole. Do not crush, break, or chew it. Take it with the morning meal.

If you take the extended-release tablet, part of the tablet may pass into your stools. This is normal and is nothing to worry about.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Store the medicine in the original container to protect it from moisture. You may also store the tablets in a pill box or pill organizer for up to 30 days only. Store at room temperature, away from heat, moisture, and direct light.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to canagliflozin or metformin, or if you have diabetic ketoacidosis (high ketones and acid in the blood).

Tell your doctor if you are pregnant. Do not use this medicine during the second and third part of your pregnancy, unless your doctor tells you to. If you had problems ovulating or have irregular periods, this medicine may cause you to ovulate, which could lead to pregnancy if you are sexually active. Talk to your doctor about effective birth control while you are using this medicine.

Do not breastfeed during treatment with this medicine.

Tell your doctor if you have kidney disease, liver disease, heart disease, blood vessel disease, adrenal or pituitary gland disease, heart failure, vitamin B12 deficiency, nerve problems, type 1 diabetes, an infection, or a history of pancreas problems, genital yeast or urinary tract infections, leg surgery, or foot ulcers. Tell your doctor if you are on a low-salt diet, if you drink alcohol, or if you are having surgery or other procedures.

This medicine may cause the following problems:Lactic acidosis (too much acid in the blood)Increased risk for leg, toe, or midfoot amputation (removal)Low blood pressureKetoacidosis (high ketones and acid in the blood), which can be life-threateningKidney problemsLow blood sugar levels, when used with other diabetes medicinesIncreased risk of genital yeast or urinary tract infections (including pyelonephritis, urosepsis)Fournier's gangrene (skin or tissue damage of the area between the anus and genitals)Increased risk for broken bones

Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may interact with the dye used for an x-ray or a CT scan.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Some medicines can affect how canagliflozin/metformin works. Tell your doctor if you are using any of the following:Acetazolamide, cimetidine, digoxin, dichlorphenamide, dolutegravir, isoniazid, lithium, morphine, nicotinic acid, quinine, ranitidine, ranolazine, rifampin, ritonavir, trimethoprim, vandetanibBirth control pillsBlood pressure medicineDiuretic (water pill, including amiloride, triamterene)Insulin or other diabetes medicineMedicine for heart rhythm changes (including procainamide, quinidine)Medicine to treat seizures (including phenobarbital, phenytoin, topiramate, zonisamide)NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)Thyroid medicine

Several other medicines may affect your blood sugar levels. Closely monitor your blood sugar levels when you start or stop another medicine while you are using canagliflozin/metformin.

If you are taking an evening dose of metformin extended-release tablets, you should skip the last dose before starting treatment with this medicine the following morning.

Limit the amount of alcohol you drink. Heavy alcohol use increases your risk for lactic acidosis.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Lightheadedness, dizziness, fainting
• Increased hunger, headache, confusion, shaking, trembling, sweating
• Fast or trouble breathing, stomach pain, nausea, vomiting, severe weakness, tiredness
• Pain, tenderness, redness, or swelling of the area between the anus and genitals, fever, unusual tiredness or weakness
• Confusion, severe weakness, uneven heartbeat, numbness in your hands, feet, or lips
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Change in how much or how often you urinate, trouble urinating, painful or difficult urination, lower back or side pain, chills
• Rapid weight gain, swelling in your hands, ankles, or feet
• Pain, tenderness, sores or ulcers, or infections on the leg or foot
• White or yellow vaginal discharge, vaginal itching or odor
• Redness, itching, pain, or swelling of the penis, bad-smelling discharge from the penis