Codeine Sulfate

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Codeine Sulfate

Drug Info for codeine sulfate

Codeine is used to relieve mild to moderate pain. It is also used, usually in combination with other medications, to reduce coughing. Codeine will help relieve symptoms but will not treat the cause of symptoms or speed recovery. Codeine belongs to a class of medications called opiate (narcotic) analgesics and to a class of medications called antitussives. When codeine is used to treat pain, it works by changing the way the brain and nervous system respond to pain. When codeine is used to reduce coughing, it works by decreasing the activity in the part of the brain that causes coughing. Codeine is also available in combination with acetaminophen (Capital and Codeine, Tylenol with Codeine), aspirin, carisoprodol, and promethazine and as an ingredient in many cough and cold medications. This monograph only includes information about the use of codeine. If you are taking a codeine combination product, be sure to read information about all the ingredients in the product you are taking and ask your doctor or pharmacist for more information.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in a safe and secure place. Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines web site:

Missed dose: This medicine is taken only when needed, so there are no special instructions for a missed dose.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. An overdose can be dangerous. Follow directions carefully so you do not get too much medicine at one time. Your doctor may also give naloxone to treat an overdose.

Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

This medicine is not for long-term use.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to codeine, or if you have severe lung or breathing problems or bowel blockage (including paralytic ileus).

This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

This medicine may cause the following problems:High risk of overdose, which can lead to deathRespiratory depression (serious breathing problem that can be life-threatening)Sleep-related breathing problems (including sleep apnea, sleep-related hypoxemia)Adrenal gland problemLow blood pressureSerotonin syndrome, when used with certain medicines

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Do not breastfeed while you are using this medicine.

Tell your doctor if you are pregnant, or if you have kidney disease, liver disease, lung or breathing problems (including sleep apnea), gallbladder disease, pancreas problems, prostate problems, underactive thyroid, stomach or bowel problems, or a history of head injury, brain tumor, depression, seizures, drug or alcohol abuse.

This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Sit or lie down if you feel dizzy. Stand up carefully.

This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.

When a mother is breastfeeding and takes codeine, there is a very small chance that this medicine could cause serious side effects in the baby. This is because codeine works differently in a few women, so their breast milk contains too much medicine. If you take codeine, be alert for these signs of overdose in your nursing baby: sleeping more than usual, trouble breastfeeding, trouble breathing, or being limp and weak. Call the baby's doctor right away if you think there is a problem. If you cannot talk to the doctor, take the baby to the emergency room or call 911.

This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Do not drink alcohol while you are using this medicine.

Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol. Tell your doctor if you are also using buprenorphine, butorphanol, nalbuphine, pentazocine, or a muscle relaxer.

Do not stop using this medicine suddenly without asking your doctor. You may need to take less and less before stopping it completely.

Some medicines can affect how codeine works. Tell your doctor if you using any of the following:Amiodarone, bupropion, carbamazepine, erythromycin, ketoconazole, mirtazapine, phenytoin, quinidine, rifampin, ritonavir, tramadol, or trazodoneBenzodiazepine medicineBlood pressure medicineDiuretic (water pill)Medicine for depression (including SNRIs, SSRIs, TCAs)Phenothiazine medicine

Do not use this medicine if you are using or have used an MAO inhibitor within the past 14 days.

  • Severe confusion, lightheadedness, dizziness, fainting
  • Extreme dizziness or weakness, shallow breathing, slow or uneven heartbeat, sweating, cold or clammy skin, seizures
  • Severe constipation, stomach pain, or vomiting
  • Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, seeing or hearing things that are not there
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Changes in skin color, dark freckles, cold feeling, tiredness, weight loss
  • Blue lips, fingernails, or skin
  • Slow or trouble breathing
  • Sleepiness
  • Mild constipation
  • Lightheadedness
  • Nausea or vomiting