( Fluorouracil )

Set Dosage Details









$1,288.96 With Free Coupon




$1,484.35 With Free Coupon




$1,501.77 With Free Coupon




$1,550.91 With Free Coupon




$1,565.67 With Free Coupon




$1,568.17 With Free Coupon




$1,585.43 With Free Coupon

Drug Info for fluorouracil

Fluorouracil cream and topical solution are used to treat actinic or solar keratoses (scaly or crusted lesions [skin areas] caused by years of too much exposure to sunlight). Fluorouracil cream and topical solution are also used to treat a type of skin cancer called superficial basal cell carcinoma if usual types of treatment cannot be used. Fluorouracil is in a class of medications called antimetabolites. It works by killing fast-growing cells such as the abnormal cells in actinic keratoses and basal cell carcinoma.

Fluorouracil is a generic drug used to treat patients with certain types of cancer. The average Fluorouracil price is about $251 for a 40 g tube of 5% topical cream. You can use our OptionRx savings offer to get a Fluorouracil discount of up to 80% at participating pharmacies near you.

  • Carac
  • Efudex
  • Fluoroplex
  • Tolak
  • On the skin

Your doctor will tell you how much medicine to use. Do not use more than directed.

This medicine is for use only on your skin. Do not get any of this medicine near or around your eyes, nose, or mouth. Rinse it off right away if it does get on these areas.

Topical application routeWash your hands with soap and water before and after you use this medicine.

Topical application routeApply a thin layer of the medicine to the affected area. Rub it in gently.

You may use a glove, nonmetal applicator, or your fingers to apply this medicine.

Topical application routeDo not cover the treated area with a bandage unless directed by your doctor.

Missed dose: Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Keep this medicine away from pets. Do not allow pets to contact the skin where the medicine is applied. Throw away or clean any cloth or applicator that may still have some of this medicine. Do not leave any medicine on your hands, clothing, carpet, or furniture.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to fluorouracil, if you are pregnant, or if you have dihydropyrimidine dehydrogenase (DPD) enzyme deficiency.

It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

Tell your doctor if you are breastfeeding or if you have other skin problems.

This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Topical application routeDo not put cosmetics or skin care products on the treated skin.

Make sure your doctor knows if you are breast feeding. Tell your doctor if you are sensitive to preservatives, or if you have any other medical conditions.

This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Diarrhea that contains blood, stomach pain, vomiting
  • Fever, chills, cough, sore throat, body aches
  • Swelling, blistering, redness, or peeling of the skin
  • Unusual bleeding, bruising, or weakness
  • Swelling, blistering, redness, or peeling of skin.
  • Pain where the medicine is put on.
  • Hair loss
  • Swelling, blistering, redness, or peeling of skin.
  • Sores or white patches on your lips, mouth, or throat
  • Eye burning, itching, stinging, or watering
  • Mild skin itching or burning.
Frequently Asked Questions

Fluorouracil intravenous solution is used to treat certain types of cancer, including colon cancer, stomach, and certain types of breast cancer. Fluorouracil works alone or in combination with other medication to reduce the spread of cancer cells in the body.

In addition to Fluorouracil, several other similar brand name drugs may be used to treat these symptoms including 5-Fluorouracil and 5-FU. Consult with your doctor to determine the best treatment for your condition.

The average Fluorouracil price without insurance is about $251 for a 40 g tube of 5% topical cream. Prices vary depending on dosage, supply needed, and pharmacy location.

Fluorouracil is a generic drug. Similar brand-name drugs include Fluorouracil Novaplus and PremierPro Rx Fluorouracil. Our free coupon may be used for savings on Fluorouracil and alternative brand-name drugs for savings of up to 80%.

Fluorouracil intravenous solution is only available in 50 mg/mL strength. Follow your doctor's instructions for dosage and use of this medication.

There are not currently any additional discount offers available for Fluorouracil. However, you can save on the retail price of this medication by asking your local pharmacy if they accept OptionRx pharmacy coupons, or check our site to find which pharmacies near you accept our savings card. OptionRx coupons offer uninsured and underinsured patients an opportunity to save. Our free coupon card is free and easy to use, and our customers usually find that they save more using our coupon instead of a manufacturer coupon.