Butorphanol Tartrate

Butorphanol is a medication used to treat pain (analgesic). This drug is a synthetic opioid which acts on areas of the brain to give pain relief. Butorphanol is a generic drug previously sold under the trade name Stadol. This drug has been available for years. In the treatment of pain, butorphanol use is fairly common.

• Belbuca
• Brixadi
• Brixadi (Weekly)
• Bunavail
• Buprenex
• Buprenorphine
• Buprenorphine HCl
• Buprenorphine HCl-Naloxone HCl
• Butorphanol Tartrate
• Butrans
• Nalbuphine HCl
• Nubain
• Pentazocine-Naloxone HCl
• Probuphine Implant Kit
• Sublocade
• Suboxone
• Talwin
• Zubsolv

• Spray

• Into the nose

Your doctor will tell you how much medicine to use. Do not use more than directed. An overdose can be dangerous. Follow directions carefully so you do not get too much medicine at one time.

Nasal routeThis medicine is for use only in the nose. Do not get any of it in your eyes or on your skin. If it does get on these areas, rinse it off right away.

To use: Blow your nose gently to clear the nostrils.Take the cap off of the bottle and remove the clip from the neck of the pump.If you are using the medicine for the first time, you will need to prime the spray pump.To do this, hold the spray bottle with your thumb on the bottom of the bottle and your index and middle fingers on the 2 flaps on the side of the pump.Push down with your index and middle fingers. Keep pumping until you see a fine spray from the bottle.Put the tip of the spray pump into your nostril.Close the other nostril with your finger and lean your head slightly forward.Sniff gently and push down on the 2 flaps to spray the medicine into your nose. Keep your mouth closed as you are breathing in.Take the spray pump out of your nostril and tilt your head back. Sniff a few more times.

Nasal routeAfter using the nasal spray, wipe the tip of the bottle with a clean tissue and put the cap back on.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Disposal: Ask your pharmacist about the best way to dispose of medicine that you do not use. After you stop using the nasal spray, unscrew the cap, rinse the bottle, and place the parts in a waste container.

Sniff gently and push down on the 2 flaps to spray the medicine into your nose. Keep your mouth closed as you are breathing in.

Take the spray pump out of your nostril and tilt your head back. Sniff a few more times.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to butorphanol or benzethonium chloride, or if you have severe lung or breathing problems (including severe asthma) or stomach or bowel blockage (including paralytic ileus).

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, high blood pressure, lung or breathing problems (including COPD, apnea), adrenal problems, pancreas problems, gallbladder problems, a recent heart attack, or a history of brain tumor, head injury, seizures, alcohol or drug abuse.

This medicine may cause the following problems:Increased risk of overdose, which can lead to deathRespiratory depression (serious breathing problem that can be life-threatening)Serotonin syndrome, when used with certain medicines

This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Sit or lie down if you feel dizzy. Stand up carefully.

This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.

This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Some medicines can affect how butorphanol works. Tell your doctor if you are using any of the following:Carbamazepine, erythromycin, ketoconazole, mirtazapine, phenytoin, rifampin, ritonavir, theophylline, tramadol, trazodoneMedicine to treat anxiety, depression, or other mental health problems (including benzodiazepine medicine, MAO inhibitor, SNRIs, SSRIs, TCAs)

Do not drink alcohol while you are using this medicine.

Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol. Tell your doctor if you are also using buprenorphine, nalbuphine, pentazocine, or a muscle relaxer.

This medicine may be habit-forming. You should not use more of it than your doctor ordered.

This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.
• Anxiety, restlessness, fast heartbeat, fever, muscle spasms, twitching, nausea, vomiting, diarrhea, seeing or hearing things that are not there
• Blue lips, fingernails, or skin
• Extreme dizziness or weakness, shallow breathing, slow or uneven heartbeat, sweating, cold or clammy skin, seizures
• Severe confusion, lightheadedness, dizziness, fainting
• Severe constipation, stomach pain
• Trouble breathing or slow breathing
• Blurred vision
• Nasal congestion
• Ringing in the ears
• Nausea or vomiting
• Blurred vision
• Trouble sleeping
• Mild constipation
• Constipation
• Bad taste in the mouth