Buprenorphine Hcl-Naloxone Hcl

( Generic Suboxone )

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Buprenorphine Hcl-Naloxone Hcl

Drug Info for buprenorphine hcl-naloxone hcl

Buprenorphine and the combination of buprenorphine and naloxone are used to treat opioid dependence (addiction to opioid drugs, including heroin and narcotic painkillers). Buprenorphine is in a class of medications called opioid partial agonist-antagonists and naloxone is in a class of medications called opioid antagonists. Buprenorphine alone and the combination of buprenorphine and naloxone work to prevent withdrawal symptoms when someone stops taking opioid drugs by producing similar effects to these drugs.

Suboxone is a medication used to treat opioid addictions (opioid dependence). Suboxone belongs to a class of medications called semi-synthetic opioids. Suboxone is the brand name of the drug buprenorphine. Suboxone also contains another drug, naloxone, which is an opioid antagonist. Suboxone was approved for use by the FDA in 2002. Reckitt Benckiser manufactures Suboxone.

  • Suboxone
  • Zubsolv
  • Into the mouth

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

You must let the medicine dissolve. Never swallow the film or tablet. Your body may not absorb enough of the medicine if you swallow it.

Your health caregiver should show you how to use the medicine. If you do not understand, ask for help. It is important to use the medicine correctly.

Do not talk while the medicine is inside your mouth.

Buccal film: Rinse your mouth with water to moisten it. Place the film against the inside of your cheek. If your doctor told you to use more than 1 film, place the second film inside your other cheek. Do not place more than 2 films inside of 1 cheek at a time. Do not move or touch the film. Do not eat or drink anything until the film is completely dissolved.

Sublingual tablet: Place the tablet under your tongue. If your doctor told you to use more than 1 tablet, place all of the tablets in different places under your tongue at the same time. You can use 2 tablets at a time until you have taken all of the medicine, if that is easier for you. Let the tablets dissolve completely in your mouth. Do not eat or drink anything until the tablets are completely dissolved. Rinse your mouth with water and swallow. Wait for at least one hour before brushing your teeth.

Do not break, crush, chew, or cut the film or tablet.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website:www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm

Sublingual film: Drink some water to help moisten your mouth. Place the film under your tongue. If your doctor told you to use more than 1 film, place the second film on the opposite side from the first one. Do not move the film after you placed it under your tongue. If you are supposed to use more than 2 films, use them the same way, but do not start until the first 2 films are completely dissolved. Do not eat or drink anything until the film is completely dissolved.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to buprenorphine or naloxone.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease (including hepatitis), lung or breathing problems (including sleep apnea), tooth problems (including history of cavities), adrenal gland problems, an enlarged prostate, trouble urinating, gallbladder problems, thyroid problems, stomach problems, or a history of depression. Tell your doctor if you have heart disease, congestive heart failure, a slow heartbeat, or a history of heart rhythm problems (including long QT syndrome). Tell your doctor if you have a brain tumor, head injury, or alcohol or drug abuse.

This medicine may cause the following problems:High risk of overdose, which can lead to deathRespiratory depression (serious breathing problem that can be life-threatening)Adrenal gland problemsSleep-related breathing problems (including sleep apnea, sleep-related hypoxemia)Low blood pressureLiver problemsQT prolongation (heart rhythm problem)Tooth problems (including tooth fracture, tooth loss)Serotonin syndrome, when used with certain medicines

This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Sit or lie down if you feel dizzy. Stand up carefully.

Tell any doctor or dentist who treats you that you are using this medicine.

This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Do not use this medicine if you are using or have used an MAO inhibitor within the past 14 days.

Some medicines can affect how buprenorphine/naloxone works. Tell your doctor if you are using the following: Carbamazepine, cyclobenzaprine, erythromycin, ketoconazole, metaxalone, mirtazapine, phenobarbital, phenytoin, rifampin, tramadol, trazodoneDiuretic (water pill)Medicine to treat depression or mental health problems (including SNRIs, SSRIs, TCAs)Medicine to treat HIV/AIDS (including atazanavir, delavirdine, efavirenz, etravirine, nevirapine, ritonavir)Phenothiazine medicineTriptan medicine to treat migraine headaches

Do not drink alcohol while you are using this medicine.

Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol. Tell your doctor if you are also using butorphanol, nalbuphine, pentazocine, or a muscle relaxer.

This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Anxiety, restlessness, fast heartbeat, fever, muscle spasms, twitching, diarrhea, seeing or hearing things that are not there
  • Blue lips, fingernails, or skin, trouble breathing
  • Changes in skin color, dark freckles, cold feeling, tiredness, weight loss
  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Trouble breathing or slow breathing
  • Toothache
  • Fast, pounding, or uneven heartbeat
  • Severe confusion, lightheadedness, dizziness, or fainting
  • Extreme dizziness, drowsiness, or weakness, slow heartbeat, sweating, seizures, cold or clammy skin
  • Stuffy or runny nose
  • Trouble sleeping
  • Headache
  • Constipation, diarrhea, nausea, vomiting, stomach upset
  • Sweating