Bromocriptine Mesylate

( Generic Parlodel )

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Bromocriptine Mesylate

Drug Info for bromocriptine mesylate

Bromocriptine (Parlodel) is used to treat symptoms of hyperprolactinemia (high levels of a natural substance called prolactin in the body) including lack of menstrual periods, discharge from the nipples, infertility (difficulty becoming pregnant) and hypogonadism (low levels of certain natural substances needed for normal development and sexual function). Bromocriptine (Parlodel) may be used to treat hyperprolactinemia caused by certain types of tumors that produce prolactin, and may shrink these tumors. Bromocriptine (Parlodel) is also used alone or with other treatments to treat acromegaly (condition in which there is too much growth hormone in the body) and Parkinson's disease (PD; a disorder of the nervous system that causes difficulties with movement, muscle control, and balance). Bromocriptine (Cycloset) is used with a diet and exercise program and sometimes with other medications to control blood sugar levels in people with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Bromocriptine (Cycloset) is not used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may develop if high blood sugar is not treated). Bromocriptine is in a class of medications called dopamine receptor agonists. It treats hyperprolactinemia by decreasing the amount of prolactin in the body. It treats acromegaly by decreasing the amount of growth hormone in the body. It treats Parkinson's disease by stimulating the nerves that control movement. The way bromocriptine works to treat diabetes is not known.

Parlodel helps to treat the symptoms of Parkinson’s disease. It acts like dopamine to relieve shakiness, stiffness, slowed movement, and unsteadiness. Parlodel is also used to treat acromegaly and hyperprolactinemia. It reduces the levels of prolactin and growth hormone in the blood. It is indicated for use by adults and adolescents 11 years and older. This medication is available as a capsule.

  • Cycloset
  • Parlodel

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Take Cycloset® within 2 hours after you wake up in the morning.

Oral routeIt is best to take this medicine with food or milk.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose. If you miss a dose of Cycloset®, skip the missed dose and wait until the next morning to take it.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to bromocriptine or similar medicines, or if you are breastfeeding. Do not use Cycloset® if you have fainting migraine headaches or if you have recently given birth (postpartum). Postpartum women with a history of heart or blood vessel disease should not use this medicine.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Tell your doctor if you are pregnant. Birth control pills may not work as well to prevent pregnancy when used with Parlodel®. Use another form of birth control (including condoms or spermicide) along with your pills. Tell your doctor right away if you think you have become pregnant while using the medicine.

Tell your doctor if you have kidney disease, liver disease, heart or blood vessel disease, high or low blood pressure, lung disease, stomach ulcers or bleeding, or a history of heart attack, stroke, seizures, or mental health problems. Tell your doctor if you have galactose intolerance, lactase deficiency, or glucose-galactose malabsorption.

This medicine may cause the following problems:Lung problemsStomach or bowel bleedingRetroperitoneal fibrosisIncreased risk for skin cancerUnusual thoughts or behaviors, including an urge to gamble or spend money, or an increased sex drive

This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you are dizzy. This is more likely to happen when you first start taking this medicine, if your dose is increased, or if you drink alcohol.

It may take 2 to 3 weeks before this medicine begins to work and your symptoms improve.

Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Some medicines can affect how bromocriptine works. Tell your doctor if you are using any of the following:Isometheptene, metoclopramide, octreotide, phenylpropanolamine, probenecid, sumatriptanBlood pressure medicineInsulin or other diabetes medicinesMedicine to treat an infection (including chloramphenicol, erythromycin, itraconazole, ketoconazole, sulfamethoxazole/trimethoprim, sulfonamides)Medicine to treat mental health problems (including clozapine, haloperidol, olanzapine, pimozide, ziprasidone, butyrophenones, thioxanthenes)Phenothiazine medicine (including chlorpromazine, perphenazine, promethazine, prochlorperazine, thioridazine)Protease inhibitor medicine to treat HIV infectionSalicylates (including aspirin)

Do not drink alcohol while you are using this medicine.

This medicine may cause the following problems:Lung problemsGastrointestinal bleedingRetroperitoneal fibrosisIncreased risk for skin cancer Unusual thoughts or behaviors

This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Stand or sit up slowly if you are dizzy. This is more likely to happen when you first start taking this medicine, if your dose is increased, or if you drink alcohol.

It may take 2 to 3 weeks before this medicine begins to work and your symptoms improve.

Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Sudden or severe headache, vision changes, seizures
  • Severe stomach pain, vomiting, black or tarry stools
  • Lightheadedness, dizziness, drowsiness, fainting
  • Fever, sweating, uneven heartbeat, muscle stiffness
  • Skin changes or growths
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, back pain, swelling of your feet, ankles, or lower legs
  • Chest pain or trouble breathing
  • Confusion, seeing, hearing, or feeling things that are not there
  • Constipation, nausea, upset stomach
  • Headache
  • Tiredness or weakness
  • Stuffy or runny nose