Amiloride-Hydrochlorothiazide

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Amiloride-Hydrochlorothiazide

Drug Info for amiloride-hydrochlorothiazide

The combination of amiloride and hydrochlorothiazide is used alone or in combination with other medications to treat high blood pressure and heart failure in patients who have low amounts of potassium in their bodies or for whom low potassium levels in the body could be dangerous. Amiloride and hydrochlorothiazide are in a class of medications called diuretics ('water pills'). They work by causing the kidneys to get rid of unneeded water and salt from the body into the urine. High blood pressure is a common condition and when not treated, can cause damage to the brain, heart, blood vessels, kidneys and other parts of the body. Damage to these organs may cause heart disease, a heart attack, heart failure, stroke, kidney failure, loss of vision, and other problems. In addition to taking medication, making lifestyle changes will also help to control your blood pressure. These changes include eating a diet that is low in fat and salt, maintaining a healthy weight, exercising at least 30 minutes most days, not smoking, and using alcohol in moderation.

  • Tablet
  • By mouth

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Swallow the tablet whole. Do not break, crush, or chew it.

Oral routeIt is best to take this medicine with food or milk.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to amiloride, hydrochlorothiazide, or sulfa drugs, you are unable to urinate, or you have kidney disease or high potassium levels (hyperkalemia).

Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease (including cirrhosis), heart disease, diabetes, gout, or lupus.

This medicine may cause the following problems:New or worsening lupusNew or worsening goutIncreased risk of skin cancer

This medicine could lower your blood pressure too much and cause you to feel dizzy or lightheaded. Sit or lie down if you feel dizzy. Stand up carefully.

Do not stop using this medicine without asking your doctor, even if you feel well. This medicine will not cure your high blood pressure, but it will help keep it in the normal range. You may have to take blood pressure medicine for the rest of your life.

This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

Tell any doctor or dentist who treats you that you are using this medicine.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Unusual bleeding or bruising

Do not use this medicine if you are also using potassium supplements or salt substitutes, or you are taking another diuretic, including spironolactone or triamterene.

Some medicines and foods can affect how this medicine works. Tell your doctor if you are taking any of the following: Cholestyramine, colestipol, cyclosporine, digoxin, dofetilide, lithium, norepinephrine, tacrolimusBlood pressure medicine (including ACE inhibitors, ARBs)Insulin or oral diabetes medicineMuscle relaxantNSAIDs (including indomethacin)Steroid medicine

Alcohol, narcotic pain relievers, or sleeping pills may cause you to feel more lightheaded, dizzy, or faint when used with this medicine. Tell your doctor if you drink alcohol or use pain relievers or sleeping pills.

Tell any doctor or dentist who treats you that you are using this medicine.

If you stop using this medicine, your blood pressure may go up. High blood pressure usually has no symptoms. Even if you feel well, do not stop using the medicine without asking your doctor.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Skin rash or itching
  • Lightheadedness or fainting
  • Dry mouth, increased thirst, muscle cramps, nausea, or vomiting
  • Severe diarrhea or stomach pain
  • Problems urinating, pain in side or lower back
  • Sores, reddish patch or irritated area, shiny bump, pink growth, or white, yellow or waxy scar-like area on the skin
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain (may be related to your disease and not a side effect)
  • Confusion, weakness, irregular heartbeat, shortness of breath, numbness or tingling in your hands, feet, or lips
  • Unusual bleeding or bruising
  • Problems having sex
  • Loss of appetite
  • Constipation, mild nausea, vomiting, diarrhea, or upset stomach