Afinitor Disperz

• Afinitor
• Afinitor Disperz
• Zortress

• Afinitor
• Afinitor Disperz
• Alecensa
• Aliqopa
• Alunbrig
• Augtyro
• Balversa
• Beleodaq
• Bortezomib
• Bosulif
• Braftovi
• Brukinsa
• Cabometyx
• Calquence
• Caprelsa
• Cometriq (100 MG Daily Dose)
• Cometriq (140 MG Daily Dose)
• Cometriq (60 MG Daily Dose)
• Copiktra
• Cotellic
• Everolimus
• Farydak
• Fotivda
• Fyarro
• Gavreto
• Gleevec
• Ibrance
• Iclusig
• IDHIFA
• Imatinib Mesylate
• Imbruvica
• Inrebic
• Istodax
• Jakafi
• Jaypirca
• Kisqali (200 MG Dose)
• Kisqali (400 MG Dose)
• Kisqali (600 MG Dose)
• Koselugo
• Krazati
• Kyprolis
• Lapatinib Ditosylate
• Lorbrena
• Lumakras
• Lynparza
• Lytgobi (12 MG Daily Dose)
• Lytgobi (16 MG Daily Dose)
• Lytgobi (20 MG Daily Dose)
• Mekinist
• Mektovi
• Nerlynx
• NexAVAR
• Ninlaro
• Ogsiveo
• Ojjaara
• PAZOPanib HCl
• Pemazyre
• Piqray (200 MG Daily Dose)
• Piqray (250 MG Daily Dose)
• Piqray (300 MG Daily Dose)
• Qinlock
• Retevmo
• Rezlidhia
• romiDEPsin
• Rozlytrek
• Rubraca
• Rydapt
• Scemblix
• SORAfenib Tosylate
• Sprycel
• Stivarga
• SUNItinib Malate
• Sutent
• Tabrecta
• Tafinlar
• Talzenna
• Tarceva
• Tasigna
• Tazverik
• Temsirolimus
• Tepmetko
• Tibsovo
• Torisel
• Truqap
• Truseltiq (100MG Daily Dose)
• Truseltiq (125MG Daily Dose)
• Truseltiq (50MG Daily Dose)
• Truseltiq (75MG Daily Dose)
• Turalio
• Tykerb
• Ukoniq
• Vandetanib
• Vanflyta
• Velcade
• Verzenio
• Vitrakvi
• Vonjo
• Votrient
• Xalkori
• Xospata
• Zejula
• Zelboraf
• Zolinza
• Zydelig
• Zykadia

• Tablet
• Tablet for Suspension

• By mouth

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep your medicine in the original package until you are ready to use it. Also, keep Zortress® tablets dry.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Take this medicine the same way every day. This means take it at the same time and always with food or always without food.

Regular tablet: Swallow whole with a glass of water. Do not crush, break, or chew it.

Tablet for suspension: Wear disposable gloves if you are mixing the medicine for another person. Dissolve the tablet in water before you take it. Do not swallow the tablet whole. After the tablet dissolves, drink the mixture within 60 minutes. If you are not able to drink it within 60 minutes, throw that dose away and prepare another one. There are 2 ways to prepare the suspension:Oral syringe: Follow the directions that came with your medicine. Dissolve the tablet inside a 10 milliliter (mL) syringe, using 5 mL of water and 4 mL of air. The tablet will take 3 minutes to dissolve. Slowly turn the syringe upside down 5 times. Place the syringe in the mouth and slowly give the dose. Fill the syringe with water and air again, and give this to the patient to make sure all of the medicine is taken. Use a new syringe for each dose.Small cup: Put the tablet in a cup with 25 mL water. Do not break or crush the tablet. Wait 3 minutes, and then gently stir the mixture. Drink the mixture right away. Refill the glass with the same amount of water and drink it right away so you get all the medicine.

Do not use the regular tablet and the tablet for suspension together. Use only 1 form of this medicine.

You may be given a mouthwash (including dexamethasone alcohol-free mouthwash) when starting Afinitor® or Afinitor® Disperz to prevent mouth sores or ulcers. Do not drink or eat food for at least 1 hour after swishing and spitting the mouthwash.

Kidney or liver transplant patients: You may have to take this medicine for the rest of your life to prevent rejection of the organ. Do not change your dose or stop taking this medicine without talking to your doctor. Take all medicines that are part of your treatment as prescribed, especially the ones you need to take at the same time as everolimus.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: Afinitor® or Afinitor® Disperz: If it is less than 6 hours from the time you normally take the dose, you may still take it. If it is more than 6 hours, skip the missed dose and go back to your regular dosing schedule. Do not take extra medicine to make up for a missed dose.Zortress®: Take the dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to everolimus or similar medicines, or if you are pregnant.

Oral routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Use an effective form of birth control during treatment with this medicine and for at least 8 weeks after your last dose. Male patients with female partners should use an effective form of birth control during treatment with Afinitor® or Afinitor® Disperz and for 4 weeks after the last dose.

Do not breastfeed during treatment with Afinitor® or Afinitor® Disperz and for 2 weeks after your last dose.

Tell your doctor if you have kidney disease, liver disease, lung or breathing problems, any type of infection (including hepatitis B), diabetes, high cholesterol, or a history of skin cancer or lymphoma. Tell your doctor if you have a lactose intolerance, Lapp lactase deficiency, or a glucose-galactose malabsorption. Also, tell your doctor if you have had a heart transplant, if you are having a surgery or other procedures, or if you had or are planning to receive a radiation treatment.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

This medicine may cause the following problems:Increased risk of cancer (including skin cancer, lymphoma)Increased risk of serious infectionsInterstitial lung disease or non-infectious pneumonitis (inflammation of the lungs)Angioedema (severe swelling, when used with an ACE inhibitor)Kidney problemsSlow wound healingDiabetesHigh cholesterol in the bloodLiver problemsIncreased risk of blood clots in the transplanted kidney or liverWorsening side effects from radiation treatmentThrombotic microangiopathy (damage in the smallest blood vessels), hemolytic uremic syndrome, and thrombotic thrombocytopenic purpura

This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.

Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Some foods and medicines can affect how everolimus works. Tell your doctor if you are using any of the following:Amprenavir, aprepitant, atazanavir, boceprevir, cannabidiol, carbamazepine, clarithromycin, cyclosporine, digoxin, diltiazem, efavirenz, erythromycin, fluconazole, fosamprenavir, indinavir, itraconazole, ketoconazole, midazolam, nefazodone, nelfinavir, nevirapine, nicardipine, octreotide, phenobarbital, phenytoin, rifabutin, rifampin, rifapentine, ritonavir, saquinavir, St John's wort, telaprevir, telithromycin, verapamil, voriconazoleBlood pressure medicineMedicine to lower cholesterol (including atorvastatin, lovastatin, pravastatin, simvastatin)Steroid medicine

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines.

Tell your doctor if you have kidney problems, liver disease, any type of infection (such as hepatitis B), diabetes, high cholesterol, or a history of skin cancer or lymphoma. Tell your doctor if you are lactose intolerant or have Lapp lactase deficiency or glucose-galactose malabsorption.

This medicine may cause the following problems:Noninfectious pneumonitisSlow wound healingKidney failureIncreased risk of skin cancer and lymphomaAngioedema (when used with an ACE inhibitor blood pressure medicine)Increased risk of blood clots in the new kidney or liver (transplant patients)

This medicine may weaken your immune system and increase your risk for infections. Tell your doctor right away if you notice any changes in your health.

Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Because this medicine increases your risk for skin cancer, wear sunscreen when you are outside. Do not use sunlamps or tanning beds. Tell your doctor if you notice any growths or changes on your skin.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Swollen glands in your neck, armpits, or groin, pain in your groin, lower back, or side
• Fever, chills, stuffy or runny nose, sore throat, body aches
• Sores, ulcers, or white patches on your lips, mouth, or throat
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blurred vision, increased hunger, thirst, or urination, unexplained weight loss
• Chest pain, trouble breathing, cough, fast, slow, uneven, or pounding heartbeat
• Decrease in how much or how often you urinate, painful urination, cloudy bloody urine
• Dark urine or pale stools, loss of appetite, nausea, vomiting, stomach pain, yellow skin or eyes
• Rapid weight gain, swelling in your hands, ankles, or feet
• Unusual bleeding, bruising, or weakness
• Diarrhea
• Headache
• Dry mouth, muscle cramps, shakiness