Segluromet

• Segluromet

• Actoplus Met
• Actoplus met XR
• Alogliptin-metFORMIN HCl
• Alogliptin-Pioglitazone
• Appformin
• Appformin-D
• Avandamet
• Avandaryl
• D-Care DM2
• Duetact
• glipiZIDE-metFORMIN HCl
• Glucovance
• glyBURIDE-metFORMIN
• Glyxambi
• Invokamet
• Invokamet XR
• Janumet
• Janumet XR
• Jentadueto
• Jentadueto XR
• Juvisync
• Kazano
• Kombiglyze XR
• Oseni
• Pioglitazone HCl-Glimepiride
• Pioglitazone HCl-metFORMIN HCl
• PrandiMet
• Qtern
• Repaglinide-metFORMIN HCl
• sAXagliptin-metFORMIN ER
• Segluromet
• Soliqua
• Steglujan
• Synjardy
• Synjardy XR
• Trijardy XR
• Xigduo XR
• Xultophy

• Tablet

• By mouth

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Oral routeIt is best to take this medicine with food or milk.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to ertugliflozin or metformin, or if you have severe kidney disease (including patients receiving dialysis).

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Tell your doctor if you are pregnant. Do not use this medicine during the second and third part of your pregnancy, unless your doctor tells you to. If you had problems ovulating or have irregular periods, this medicine may cause you to ovulate, which could lead to pregnancy if you are sexually active. Talk to your doctor about effective birth control while you are using this medicine.

This medicine may cause the following problems:Lactic acidosis (too much acid in the blood)Low blood pressureKetoacidosis (high ketones and acid in the blood), which can be life-threateningKidney problemsIncreased risk of genital yeast or urinary tract infectionsIncreased risk for lower leg or foot amputation (removal)Low blood sugar, when used with other diabetes medicineFournier's gangrene (skin or tissue damage of the area between the anus and genitals)

Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests. You may need to stop taking this medicine at least 4 days before a surgery.

Tell your doctor if have kidney disease, liver disease, heart failure, blood vessel disease, nerve problems, adrenal or pituitary gland problem, vitamin B12 deficiency, or a history of pancreas problems, leg surgery or foot ulcers, or urinary tract or genital yeast infections. Tell your doctor if you are on a low-salt diet, if you drink alcohol, or if you are having a surgery or other procedures.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may interact with the dye used for an x-ray or a CT scan.

This medicine may cause some patients to become dehydrated. Drink plenty of water every day, during exercise, or in hot weather.

Do not breastfeed during treatment with this medicine.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Limit the amount of alcohol you drink. Heavy alcohol use or binge drinking increases your risk for lactic acidosis.

Some medicines can affect how ertugliflozin/metformin works. Tell your doctor about all other medicines that you are using, including the following:Acetazolamide, cimetidine, dichlorphenamide, dolutegravir, isoniazid, lithium, nicotinic acid, phenytoin, ranolazine, vandetanib, zonisamideBirth control pills (including estrogen)Blood pressure medicineDiuretic (water pill)Insulin or another diabetes medicineMedicine to treat mental illnessNSAID pain or arthritis medicine (including aspirin, diclofenac, ibuprofen, naproxen)Phenothiazine medicineSteroid medicineThyroid medicine

Several other medicines may affect your blood sugar levels. Closely monitor your blood sugar levels when you start or stop another medicine while you are using ertugliflozin/metformin.

• Shaking, trembling, sweating, fast or pounding heartbeat, hunger, confusion
• Change in how much or how often you urinate, bloody urine, difficult or painful urination, lower back or side pain, chills
• Pain, tenderness, sores or ulcers, or infections on the leg or foot
• Lightheadedness, dizziness, fainting, drowsiness
• Fast or trouble breathing, muscle pain
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Pain, tenderness, redness, or swelling of the genitals or in the area between the anus and genitals, fever, unusual tiredness or weakness
• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
• Headache
• Diarrhea, passing gas, stomach upset
• White or yellow vaginal or penile discharge, vaginal or penile itching or odor