Revlimid

( Lenalidomide )

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Lenalidomide

Drug Info for lenalidomide

Lenalidomide is used to treat a certain type of myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and does not produce enough healthy blood cells). Lenalidomide is also used along with dexamethasone to treat people with multiple myeloma (a type of cancer of the bone marrow). It is also used to treat people with multiple myeloma after a hematopoietic stem-cell transplant (HSCT; procedure in which certain blood cells are removed from the body and then returned to the body). Lenalidomide is also used to treat people with mantle cell lymphoma (a fast-growing cancer that begins in the cells of the immune system) who have been treated with bortezomib (Velcade) and at least one other medication. Lenalidomide should not be used to treat people with chronic lymphocytic leukemia (a type of cancer of the white blood cells that gets worse slowly over time) unless they are participating in a clinical trial (research study to see whether a medication may be used safely and effectively to treat a certain condition). Lenalidomide is in a class of medications called immunomodulatory agents. It works by helping the bone marrow to produce normal blood cells and by killing abnormal cells in the bone marrow.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Take this medicine at the same way each day. Take it at the same time and take it consistently, either with or without food.

Swallow the capsule whole with water. Do not crush, break, chew, or open it.

Do not open the capsules or handle them any more than needed. If you accidentally touch the powder inside the capsule, wash your skin with soap and water right away. If it gets into your eyes, nose, or mouth, rinse right away with water.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: Less than 12 hours since your regular time: Take the missed dose as soon as you can. Then, take your next dose at the normal time.More than 12 hours since your regular time: Skip the missed dose. Take your next dose at the normal time. Do not use extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Return unused capsules to your doctor or pharmacist.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to lenalidomide, or if you are pregnant.

This medicine will cause birth defects if either partner is using it during conception or pregnancy. Call your doctor for emergency birth control information if you think you or your sexual partner becomes pregnant.

Women should begin using 2 forms of reliable birth control 4 weeks before starting treatment. Continue using birth control during treatment with this medicine and for at least 4 weeks after the last dose. Routine pregnancy tests are needed.

Men, even those who have had a vasectomy, must prevent pregnancy in their sexual partners during treatment with this medicine and for at least 4 weeks after the last dose. Do not donate sperm while using this medicine.

Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, lactose intolerance, high blood pressure, high cholesterol, thyroid problems, or a history of heart attack or stroke. Tell your doctor if you smoke.

Do not donate blood during treatment and for at least 4 weeks after the last dose.

This medicine may cause the following problems:Increased risk of blood clots, heart attack, or strokeIncreased risk of new cancerLiver problemsSerious skin reactionsDrug reaction with eosinophilia and systemic symptoms (DRESS), which can damage organs including the liver, kidney, or heartTumor lysis syndrome (metabolic problem that can be life-threatening)Worsening of your tumor (tumor flare reaction)Thyroid problems

This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Do not receive pembrolizumab together with dexamethasone and lenalidomide or similar medicines if you have multiple myeloma.

Some medicines can affect how lenalidomide works. Tell your doctor if you are using any of the following:Darbepoetin alfa, digoxin, epoetin alfaBlood thinner (including warfarin)Medicine that contains estrogen

Men, even those who have had a vasectomy, must prevent pregnancy in their sexual partners during therapy and for 4 weeks after the last dose. Do not donate sperm while using this medicine.

Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, lactose intolerance, high blood pressure, high cholesterol, or a history of heart attack or stroke. Tell your doctor if you smoke.

Do not donate blood during therapy or for 1 month after the last dose.

This medicine may cause the following problems:Increased risk of blood clots, heart attack, or strokeIncreased risk of new cancerSerious liver problemsSerious skin reactionsTumor lysis syndromeWorsening of your tumor (tumor flare reaction)

This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
  • Unusual bleeding, bruising, or weakness
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Numbness or weakness on one side of your body, sudden or severe headache, pain in your lower leg, problems with vision, speech, or walking
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, or red skin rash
  • Change in how often you urinate, uneven heartbeat, seizure
  • Chest pain that may spread, trouble breathing, nausea, unusual sweating, fainting
  • Fever, chills, cough, sore throat, body aches
  • Swollen lymph glands, low fever, pain, rash
  • Dizziness, trouble sleeping, tiredness
  • Diarrhea, constipation
  • Rapid weight gain, swelling in your hands, ankles, or feet
  • Joint, back, or muscle pain