Premphase

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CVS PHARMACY
$218.79 With Free Coupon
SAFEWAY PHARMACY Retail

$280.99

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20%

$225.56 With Free Coupon
WALGREENS
$226.08 With Free Coupon
WALMART PHARMACY
$227.48 With Free Coupon
WEGMANS FOOD MARKETS INC Retail

$280.99

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18%

$230.19 With Free Coupon
HARRIS TEETER PHARMACY
$231.92 With Free Coupon
GIANT PHARMACY
$249.28 With Free Coupon
CVS PHARMACY #
$249.46 With Free Coupon
AKINA PHARMACY
$258.47 With Free Coupon
MY DR'S PHARMACY
$258.47 With Free Coupon
HARRIS TEETER
$259.87 With Free Coupon
HEALTH STAR PHARMACY
$259.87 With Free Coupon
LIBERTY PHARMACY & MEDICAL SUPPLIES
$259.87 With Free Coupon
LOUDOUN COMMUNITY PHARMACY
$259.87 With Free Coupon
WEGMANS FOOD MARKETS, INC.
$259.87 With Free Coupon
RX+PHARMACY
$259.87 With Free Coupon
Premphase

Drug Info for premphase

Estrogen is used to treat hot flushes ('hot flashes'; sudden strong feelings of heat and sweating) in women who are experiencing menopause ('change of life', the end of monthly menstrual periods). Some brands of estrogen are also used to treat vaginal dryness, itching, or burning, or to prevent osteoporosis (a condition in which the bones become thin and weak and break easily) in women who are experiencing or have experienced menopause. However, women who need a medication only to treat vaginal dryness or only to prevent osteoporosis should consider a different treatment. Some brands of estrogen are also to relieve symptoms of low estrogen in young women who do not produce enough estrogen naturally. Some brands of estrogen are also used to relieve the symptoms of certain types of breast and prostate (a male reproductive gland) cancer. Estrogen is in a class of medications called hormones. It works by replacing estrogen that is normally produced by the body.

Premphase is used to treat symptoms caused by menopause, and it is also used to prevent osteoporosis in certain patients. There is not a generic version of this drug available. The average Premphase cash price can be expensive at about $232 for one pack of Premphase tablets. However, you can save up to 80% off of your Premphase cost by using our free Premphase savings card at pharmacies near you that participate with OptionRx.

  • Premarin
  • Premphase

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Take this medicine at the same time each day.

Your doctor may want you to take calcium or vitamin D supplements while you take this medicine.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

This medicine is not right for everyone. Do not use it if you had a severe allergic reaction to estrogens, you have liver disease, cancer of the breast, uterus, or ovaries, or a history of blood clotting problems, heart attack, or stroke. Do not use it if you may be pregnant, are breastfeeding, or have unusual vaginal bleeding that has not been checked by a doctor.

Tell your doctor if you have endometriosis or a history of cancer. Tell your doctor if you have asthma, diabetes, epilepsy, gallbladder, heart, or kidney disease, high or low calcium, lupus, migraine headaches, porphyria, or thyroid problems. Tell your doctor if you have high blood pressure, high cholesterol, a family history of high cholesterol, or a history of liver problems caused by pregnancy or estrogen.

This medicine may increase your risk for the following: DementiaHeart attack, blood clots, or stroke, especially if you smoke, have diabetes or high cholesterol, or are overweightBreast or ovarian cancerUterine cancer if you take this medicine without a progestin medicine

It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

Stop taking this medicine and check with your doctor immediately if you have a severe headache or sudden loss of vision or vision changes. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Pelvic exam, breast exam, and mammogram (breast x-ray) may be needed to check for side effects.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Yellow skin or eyes

Some medicines can affect how estrogens work. Tell your doctor if you are taking a blood thinner (such as warfarin), thyroid replacement medicine, or other female hormones.

This medicine may increase your risk for the following: DementiaHeart attack, blood clots, or stroke, especially if you smoke, have diabetes or high cholesterol, or are overweightBreast or ovarian cancerUterine cancer if you take this medicine without a progestin medicine

Tell your doctor if you have endometriosis or a history of cancer. Tell your doctor if you have asthma, diabetes, epilepsy, gallbladder, heart, or kidney disease, high or low calcium, lupus, migraine headaches, porphyria, or thyroid problems. Tell your doctor if you have high blood pressure, high cholesterol, a family history of high cholesterol, or a history of liver problems caused by pregnancy or estrogen.

Stop taking this medicine and check with your doctor immediately if you have a severe headache or sudden loss of vision or vision changes. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Pelvic exam, breast exam, and mammogram (breast x-ray) may be needed to check for side effects.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Numbness or weakness on one side of your body, sudden or severe headache, problems with vision, speech, or walking
  • Swelling in your face, hands, ankles, or feet
  • Seizures
  • Pain in your calf
  • Unusual vaginal bleeding
  • Yellow skin or eyes
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, trouble breathing, or coughing up blood
  • Breast changes, lumps, or discharge (in women or men)
  • Change in weight or hair growth
  • Breast pain or tenderness
  • Nausea, vomiting, stomach pain, bloating
Frequently Asked Questions

Premphase is an estrogen/progestin combination drug that can treat hot flashes, vaginal dryness, and other symptoms caused by menopause. It can also be used to prevent osteoporosis in women after menopause. Premphase works by replacing estrogen and progestin in the body when the body does not make enough of these hormones on its own. This drug is approved for use in adult patients.

A similar drug to Premphase is Prempro. Consult with your doctor for more information on these drugs and alternative drug options to determine the best treatment for you.

The average Premphase price without insurance is about $232 for one pack of 28 Premphase biphasic oral tablets (which is the equivalent of a one-month supply). Prices may vary depending on the dosage and the pharmacy location.

There is not currently a generic version of Premphase available. However, you can save significantly on your Premphase cost with our free discount card.

Premphase is an oral tablet available in the following strengths: 0.625 mg-2.5 mg, 0.45 mg-1.5 mg, 0.3 mg-1.5 mg, 0.625 mg-5 mg, and biphasic. Follow your doctor's instructions for using this medication.

Eligible patients may save between 36% and 75% off of this drug with the Pfizer RxPathways Savings Card. Underinsured and uninsured patients may also qualify to receive Premphase for free or at a savings via the Pfizer Patient Assistance Program and the HealthWell Foundation Copay Program. Contact these programs for more information. You can also use our coupon. Our customers typically find that they save more using our coupon instead of manufacturer coupons.