Polymyxin B Sulfate

• PremierPro Rx Polymyxin B

• Colistimethate Sodium (CBA)
• Coly-Mycin M
• Polymyxin B Sulfate

• Injectable

• By injection

Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

A nurse or other trained health professional will give you this medicine.

This medicine is given as a shot into a muscle or a vein. It can also be given as a shot into your back.

Missed dose: Call your doctor or pharmacist for instructions. This medicine needs to be given on a fixed schedule.

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to polymyxin.

Trouble breathing

Fever with a headache or stiff neck

Dizziness, drowsiness, or irritability

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease.

This medicine may cause the following problems:Kidney problemsNerve problems

This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

Call your doctor if your symptoms do not improve or if they get worse.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Tell your doctor if you recently had surgery or a procedure that included the use of anesthesia. The muscle relaxers and anesthetics used may interact with polymyxin B.

Tell your doctor if you are taking or have recently taken another antibiotic, such as bacitracin, streptomycin, neomycin, kanamycin, gentamicin, tobramycin, or amikacin. You could have a higher risk of side effects if you take any of these with polymyxin B.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

Call your doctor if your symptoms do not improve or if they get worse.

• Dizziness, drowsiness, or irritability
• Trouble breathing
• Diarrhea that may contain blood
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Blurred vision
• Decrease in how much or how often you urinate, bloody or cloudy urine, trouble urinating
• Fever with a headache or stiff neck
• Clumsiness, weakness, numbness, tingling feeling
• White spots in your mouth or throat, vaginal itching, or unusual vaginal discharge
• Redness, pain, swelling, or a lump under your skin where the shot was given