Opsumit

Opsumit is used in adults for the treatment of pulmonary arterial hypertension. It works by widening the blood vessels and lowering blood pressure in the lungs. Opsumit helps your heart work more efficiently and improves your ability to exercise. It also slows the progression of your condition. It is available as a tablet.

• Opsumit

• Ambrisentan
• Bosentan
• Letairis
• Opsumit
• Tracleer

• Tablet

• By mouth

Your doctor will tell you how much medicine to use. Do not use more than directed.

Swallow the tablet whole. Do not crush, break, or chew it.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

This medicine is not right for everyone. Do not use it if you are pregnant or breastfeeding.

This medicine may affect a man's ability to father a child by decreasing the amount of sperm made. Talk with your doctor before you use this medicine if you plan to have children.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. You must use 2 forms of effective birth control to avoid pregnancy while you use this medicine and for at least 1 month after you stop taking the medicine.

You must have a negative pregnancy test before you start using this medicine and every month during your treatment. Tell your doctor right away if you think you have become pregnant.

Tell your doctor if you have liver problems, anemia, or heart disease.

This medicine may cause the following problems:Liver problemsAnemiaFluid retention (body swelling)Pulmonary edema (excess fluid in the lungs)

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Some medicines can affect how macitentan works. Tell your doctor if you are using amiodarone, fluconazole, ketoconazole, rifampin, or ritonavir.

You must have a negative pregnancy test before you start using this medicine and every month during your treatment. Tell your doctor right away if you think you have become pregnant.

Tell your doctor if you have liver problems or anemia.

This medicine may cause the following problems:Liver problemsAnemiaPulmonary edema

This medicine may affect a man's ability to father a child by decreasing the amount of sperm made. Talk with your doctor before you use this medicine if you plan to have children.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes
• Trouble breathing
• Fever, chills, cough, stuffy or runny nose, sore throat, body aches
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Change in how much or how often you urinate, lower back or side pain
• Rapid weight gain, swelling in your hands, ankles, or feet
• Unusual bleeding, bruising, or weakness
• Headache
• Stuffy or runny nose, sore throat