Olanzapine-Fluoxetine Hcl

( Generic Symbyax )

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Olanzapine-Fluoxetine Hcl

Drug Info for olanzapine-fluoxetine hcl

Fluoxetine is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), some eating disorders, and panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks). Fluoxetine is also used to relieve the symptoms of premenstrual dysphoric disorder, including mood swings, irritability, bloating, and breast tenderness. It is also used along with olanzapine (Zyprexa) to treat depression that did not respond to other medications and episodes of depression in people with bipolar I disorder (manic-depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods). Fluoxetine is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.

Symbyax comes in capsule form and is used to treat depression caused by bipolar disorder. Symbyax is a combination drug that contains fluoxetine and olanzapine. Fluoxetine is an antidepressant and olanzapine is an antipsychotic medication. They work by helping to restore the balance of certain natural substances in the brain. Symbyax should not be given to a child younger than 10 years old. Common Symbyax side effects may include increased appetite, weight gain, trouble concentrating, feeling tired and vision changes.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you. It is best to take this medicine in the evening.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

This medicine is not right for everyone. Do not use it if you have had an allergic reaction to olanzapine or fluoxetine.

Tell your doctor if you are pregnant, or if you have liver disease, bleeding problems, diabetes, high cholesterol, glaucoma, prostate problems, problems with passing urine, breast cancer, mania, seizures, or severe constipation. Tell your doctor if you have had a heart rhythm problem (including QT prolongation), or if you have had a heart attack, heart failure, low blood pressure, or a stroke.

Do not breastfeed while you are using this medicine.

For some children, teenagers, and young adults, this medicine may increase mental or emotional problems. This may lead to thoughts of suicide and violence. Talk with your doctor right away if you have any thoughts or behavior changes that concern you. Tell your doctor if you or anyone in your family has a history of bipolar disorder or suicide attempts.

This medicine may cause the following problems:Changes in behavior or moodDrug reaction with eosinophilia and systemic symptoms (DRESS)Neuroleptic malignant syndrome (a nerve and muscle problem)High blood sugar, cholesterol, or triglyceride levelsSerotonin syndrome (may be life-threatening when used with certain other medicines)Tardive dyskinesia (a muscle problem that may become permanent)Higher risk of bleedingHeart rhythm changesSexual problems

This medicine may make you dizzy or drowsy, or may cause trouble with thinking or controlling body movements, which may lead to falls, fractures or other injuries. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

This medicine may make it more difficult for your body to cool down. Be careful to not become overheated during exercise or hot weather, because you could have heat stroke.

Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Trouble sleeping, unusual dreams

Unusual behavior, thoughts of hurting yourself or others

Unusual bleeding or bruising

Do not use this medicine together with pimozide or thioridazine. Do not use this medicine within 14 days of using an MAO inhibitor (MAOI), and do not start an MAOI for at least 5 weeks after you stop using fluoxetine.

Some medicines can affect how olanzapine/fluoxetine works. Tell your doctor if you are using any of the following:Buspirone, carbamazepine, clozapine, diazepam, digitoxin, dolasetron, fentanyl, fluvoxamine, haloperidol, levodopa, lithium, mefloquine, meperidine, methadone, omeprazole, pentamidine, phenytoin, probucol, rifampin, St John's wort, tacrolimus, tramadol, vinblastineAmphetamineBlood pressure medicineBlood thinner (including warfarin)Diuretic (water pill)Medicine for heart rhythm problems (including amiodarone, flecainide, procainamide, propafenone, quinidine, sotalol)Medicine to treat mental health problems (including chlorpromazine, droperidol, iloperidone, ziprasidone)Medicine to treat infections (including erythromycin, gatifloxacin, moxifloxacin, sparfloxacin)NSAID pain or arthritis medicine (including aspirin, celecoxib, diclofenac, ibuprofen, naproxen)Triptan medicine to treat migraine headachesTryptophan supplements

Do not drink alcohol while you are using this medicine.

Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine may make it more difficult for your body to cool down. Be careful to not become overheated during exercise or hot weather, because you could have heat stroke.

Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Feeling very thirsty or hungry, change in how much or how often you urinate
  • Lightheadedness, dizziness, fainting
  • Red, swollen skin, trouble breathing, yellow skin or eyes
  • Seizures or tremors
  • Loss in sexual ability, desire, drive, or performance, delayed or inability to have an orgasm, inability to have or keep an erection
  • Fever, chills, cough, sore throat, and body aches
  • Painful, prolonged erection of your penis
  • Jerky muscle movement you cannot control (often in your face, tongue, or jaw)
  • Unusual bleeding or bruising
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Anxiety, restlessness, fever, sweating, muscle spasms, nausea, vomiting, diarrhea, seeing or hearing things that are not there
  • Confusion, weakness, and muscle stiffness or twitching
  • Eye pain, trouble seeing
  • Fast, pounding, or uneven heartbeat
  • Unusual behavior, thoughts of hurting yourself or others, trouble sleeping, unusual dreams
  • Trouble swallowing
  • Constipation, increased appetite, weight gain
  • Weight gain, increased appetite
  • Dry mouth
  • Sleepiness or unusual drowsiness