Novoeight

• Advate
• Adynovate
• Afstyla
• Altuviiio
• Eloctate
• Esperoct
• Hemofil M
• Jivi
• Koate
• Koate-DVI
• Kogenate FS
• Kovaltry
• Novoeight
• Nuwiq
• Obizur

• Advate
• Adynovate
• Afstyla
• Alphanate
• Alphanate/VWF Complex/Human
• AlphaNine SD
• Alprolix
• Altuviiio
• Balfaxar
• Bebulin
• BeneFIX
• Coagadex
• Corifact
• Eloctate
• Esperoct
• Feiba
• Feiba NF
• Feiba VH Immuno
• Fibryga
• Helixate FS
• Hemgenix
• Hemlibra
• Hemofil M
• Humate-P
• Idelvion
• Ixinity
• Jivi
• Kcentra
• Koate
• Koate-DVI
• Kogenate FS
• Kogenate FS Bio-Set
• Kovaltry
• Monoclate-P
• Mononine
• Novoeight
• NovoSeven RT
• Nuwiq
• Obizur
• Profilnine
• Rebinyn
• Recombinate
• RiaSTAP
• Rixubis
• Roctavian
• Sevenfact
• Tretten
• Vonvendi
• Wilate
• Xyntha
• Xyntha Solofuse

• Injectable

• By injection

Each brand of medicine has different storage instructions. Follow the directions for your brand. Most brands need to be stored in the refrigerator. Some brands can be stored at room temperature for 3 to 12 months. Ask your doctor or pharmacist if you are not sure how to store your brand. Do not use this medicine after the expiration date.

Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

Injection routeA nurse or other health provider will give you this medicine.

Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

Adynovate®: Swirl the vial gently to dissolve the powder. Do not shake. Do not use the mixed liquid if it is cloudy or has particles in it.Use the mixed liquid within 3 hours. Do not store or refrigerate it. Throw away any unused medicine after 3 hours.

Obizur®: To prepare the medicine using 1 vial and 1 prefilled syringe: Take the vial and prefilled syringe out of the refrigerator and warm them to room temperature.Wipe the rubber stopper with an alcohol swab and allow them to dry.Peel the lid of the vial adapter. Keep the vial on a flat surface. Hold the vial with one hand and using the other hand, connect the syringe into the vial by pushing the tip onto the luer lock (tip) in the center of the vial, turn it clockwise until secured.On a flat surface, place the vial adapter over the vial and push the filter spike of the adapter into the center of the vial's rubber until the clear plastic cap snaps into the vial.Slowly push down on the plunger to inject all liquid from the syringe into the vial. Swirl the bottle gently to dissolve the medicine.Check the mixture to make sure it is clear and colorless. Do not use the medicine if you can see particles in it.Gently unscrew the syringe from the vial by turning it counter clockwise.Give the injection as directed by your doctor.

Missed dose: It is important that you use this medicine according to your schedule. If possible, have other family members trained to give your treatment in case you cannot give it to yourself.If you do miss a dose, ask your doctor or home health caregiver for instructions. Do not use extra medicine to make up for a missed dose.

Injection routeUse a new needle and syringe each time you inject your medicine.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Injection routeIf you store this medicine at home, keep it in the refrigerator. Do not freeze. Keep it in its original container. Protect from light. Do not place it back in the refrigerator if you store it at room temperature.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to antihemophilic factor (AHF), Tris, mannitol, trehalose, glutathione, polysorbate 80, or hamster or mouse proteins, or if you have congenital (from birth) hemophilia A.

Tell your doctor if you are pregnant or breastfeeding, or if you have heart or blood vessel disease or von Willebrand disease.

AHF may be made from donated human blood. Some human blood products have transmitted viruses, although the risk is low because donors and blood are both tested for viruses. AHF products that are not taken from human blood are also available. Talk with your doctor if you have concerns.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Tell your doctor if this medicine does not prevent or stop bleeding as expected.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Tell your doctor if you are pregnant or breastfeeding, or if you have heart or blood vessel disease or von Willebrand disease. Also tell your doctor if you are allergic to hamsters or mice.

AHF may be made from donated human blood. Some human blood products have transmitted viruses, although the risk is low because donors and blood are both tested for viruses. AHF products that are not taken from human blood are also available. Talk with your doctor if you have concerns.

Call your doctor if you continue to have bleeding problems after you use this medicine, or if your medicine does not seem to be working as well as usual.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Fever
• Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
• Pain, itching, burning, swelling, or a lump under your skin where the needle is placed
• Nausea
• Headache