Morphine Sulfate

Set Dosage Details





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Morphine Sulfate

Drug Info for morphine sulfate

Morphine is used to relieve moderate to severe pain. Morphine extended-release tablets and capsules are only used to relieve severe (around-the-clock) pain that cannot be controlled by the use of other pain medications. Morphine extended-release tablets and capsules should not be used to treat pain that can be controlled by medication that is taken as needed. Morphine is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain.

Morphine is an opiate medication used to treat pain. Morphine works directly on the central nervous system to decrease the sensation of pain. Morphine is a generic medication also available under the trade names Duramorph, DepoDur, Astramorph, and Infumorph. Morphine was first developed and marketed as a medicine in the early 1800s. In the treatment of pain, morphine use is very common.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

An overdose can be dangerous. Follow directions carefully so you do not get too much medicine at one time.

Oral routeIt is best to take this medicine with food or milk.

Capsule: If you cannot swallow the capsule whole, you may open it and mix the medicine pellets with a small amount of applesauce, pudding, juice, or water. Swallow the mixture right away, without chewing or crushing the pellets.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: If you miss a dose of this medicine, skip the missed dose and take your next dose at your usual time the next day. Do not double doses.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Store the medicine in a safe and secure place. Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website:

Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to morphine, codeine, hydrocodone, dihydrocodeine, or oxycodone, or you have severe lung or breathing problems or paralytic ileus.

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, low blood pressure, breathing problems or lung disease (such as asthma or COPD), Addison's disease, gallbladder problems, pancreas problems, thyroid problems, an enlarged prostate, trouble urinating, or stomach or bowel problems. Tell your doctor if you have a history of head injury, brain tumor, depression, seizures, or alcohol or drug abuse.

This medicine may cause the following problems:High risk of overdose, which can lead to deathRespiratory depression (serious breathing problem that can be life-threatening)Serotonin syndrome (when used with certain medicines)

This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

This medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.

This medicine may make you dizzy, drowsy, or lightheaded. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Do not use this medicine if you are using or have used an MAO inhibitor within the past 14 days.

Some medicines can affect how morphine works. Tell your doctor if you are using any of the following:Cimetidine, mirtazapine, quinidine, tramadol, trazodone, or verapamilDiuretic (water pill)Medicine to treat depressionPhenothiazine medicineTriptan medicine to treat migraine headaches

Do not drink alcohol while you are using this medicine.

Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol. Tell your doctor if you are also using buprenorphine, butorphanol, nalbuphine, pentazocine, a benzodiazepine, or a muscle relaxer.

This medicine may cause constipation, especially with long-term use. Ask your doctor if you should use a laxative to prevent and treat constipation.

  • Trouble breathing or slow breathing
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Anxiety, restlessness, fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, seeing or hearing things that are not there
  • Blue lips, fingernails, or skin
  • Severe confusion, lightheadedness, dizziness, or fainting
  • Extreme dizziness or weakness, shallow breathing, slow or uneven heartbeat, sweating, cold or clammy skin, seizures
  • Severe constipation, stomach pain, or vomiting
  • Nausea or vomiting
  • Mild sleepiness or tiredness
  • Mild constipation, nausea, or vomiting