Invega Sustenna

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$3,327.14 With Free Coupon
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$3,606.73 With Free Coupon
$3,606.73 With Free Coupon
$3,606.73 With Free Coupon
$3,606.73 With Free Coupon
$3,606.73 With Free Coupon
$3,606.73 With Free Coupon
Invega Sustenna

Drug Info for invega sustenna

Paliperidone extended-release injections (Invega Hafyera, Invega Sustenna, Invega Trinza) are used to treat schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Paliperidone extended-release injection (Invega Sustenna) is also used alone or with other medications to treat schizoaffective disorder (a mental illness that causes both a loss of contact with reality and mood problems [depression or mania]). Paliperidone extended-release injection is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.

Invega Sustenna treats schizophrenia and schizoaffective disorder. There is not a generic version of Invega Sustenna currently available on the market in the U.S. For a supply of 1 mL of Invega Sustenna injection (156mg/ml), the average cost is $1,964. However, you can use our free OptionRx coupon card to reduce the Invega Sustenna price at a participating pharmacy near you.

  • Invega Hafyera
  • Invega Sustenna
  • Invega Trinza
  • By injection

Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles. It is usually given in the arms or buttocks.

Injection routeA nurse or other health provider will give you this medicine.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to paliperidone or risperidone.

Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, diabetes, Parkinson disease, dementia, trouble swallowing, or a history of breast cancer, seizures, or neuroleptic malignant syndrome. Tell your doctor if you have blood vessel or heart problems, low blood pressure, heart failure, heart rhythm problems, or a history of a heart attack or stroke.

This medicine may cause the following:Increased risk of strokeNeuroleptic malignant syndrome (a nerve disorder that could be life-threatening)Heart rhythm problem (including QT prolongation)Tardive dyskinesia (a muscle disorder that could become permanent)High blood sugar or high cholesterol levelsLow blood pressureIncreased levels of prolactin hormoneIncreased risk of seizures

This medicine may make you dizzy or drowsy, or may cause trouble with thinking or controlling body movements, which may lead to falls, fractures, or other injuries. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. You may also feel lightheaded when suddenly getting up from a lying or sitting position, so stand up slowly.

This medicine lowers the number of white blood cells. This weakens your immune system, so you may get infections more easily. Wash your hands often. Avoid people who are sick.

This medicine may change how your body regulates temperature. Avoid activities that could cause you to become very cold, hot, or dehydrated.

Talk with your doctor before using this medicine if you plan to have children. Some women who use this medicine have become infertile (unable to have children).

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Painful, prolonged erection of your penis


Twitching or muscle movements you cannot control (often in your face, tongue, or jaw)

Unusual bleeding, bruising, or weakness

Some medicines can affect how paliperidone works. Tell your doctor if you are using any of the following:Bromocriptine, carbamazepine, levodopa, paroxetine, pramipexole, rifampin, ropinirole, St John's wortAntibiotic medicine (including gatifloxacin, moxifloxacin)Blood pressure medicineDiuretic (water pill)Medicine for heart rhythm problems (including amiodarone, procainamide, quinidine, sotalol)Medicine for mental illness (including chlorpromazine, thioridazine)Nitrate medicine

Do not drink alcohol while you are using this medicine.

Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

This medicine may affect how your body regulates temperature. Use caution during exercise or other activities that may cause you to become too hot. Drink plenty of liquids to avoid dehydration.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Sudden or severe headache, problems with vision, speech, or walking
  • Fast, slow, pounding, or uneven heartbeat
  • Lightheadedness, dizziness, fainting
  • Prolonged or painful erection, which lasts for more than 4 hours (in males)
  • Jerky muscle movements you cannot control (often in the face, tongue, or jaw)
  • Fever, confusion, sweating, muscle stiffness, loss of consciousness, trouble breathing
  • Unusual bleeding, bruising, or weakness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chills, cough, sore throat, body aches
  • Difficulty swallowing (that can cause food or liquid to get into your lungs)
  • Numbness or weakness in your arm or leg, or on one side of your body
  • Tremors or seizures
  • Mild headache
  • Anxiety, restlessness
  • Pain, itching, burning, swelling, or a lump under your skin where the shot was given
  • Weight gain
  • Swelling of the breasts or unusual milk production
  • Sleepiness or unusual drowsiness
Frequently Asked Questions

Invega Sustenna is a long-acting medication used to treat schizophrenia and schizoaffective disorder. It is administered via injection once-monthly. It is a type of medication called antipsychotic because it affects the chemicals in the brain. Invega Sustenna can help decrease mood disorders and hallucinations while improving the patient’s mental well-being.

While there are other drugs available on the market that also work to treat schizophrenia, there are not currently any drugs similar to Invega Sustenna available in the U.S.

The average Invega Sustenna cost depends on your insurance coverage and the pharmacy where you shop. For a supply of 0.25 mLs of Invega Sustenna injection (39 mg/0.25 mL), the average cost is $1,964.

There is not a generic version of Invega Sustenna currently available on the market in the U.S. Use OptionRx’s free coupon card to help save on the high Invega Sustenna costs.

Invega Sustenna is injected once-monthly in the patient’s arm or buttocks. The available dosage strengths are 39 mg, 78 mg, 117 mg, 156 mg, 234 mg. Follow your doctor's instructions for dosage and use of this medication.

There are several ways to save on the Invega Sustenna cost. Through the Johnson & Johnson Patient Assistance Foundation uninsured patients can receive their prescriptions for free. There is also an Invega Sustenna Instant Savings Program where insured patients may be eligible to pay no more than $10 for each prescription with up to $6,000 a year in savings. Contact these programs directly for more information. You can also use our free coupon. Our customers typically find that they save more by using our OptionRx savings card.