Increlex

Increlex is an injectable form of insulin that treats children over 2 years old with severe primary IGF-1 deficiency. Increlex works to enhance the low levels of IGF-1, a hormone that is produced naturally in the body and is responsible for the growth of muscles and bones.

• Increlex

• Increlex

• Injectable

• By injection

Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

Injection routeA nurse or other health provider will give you this medicine.

Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

Injection routeUse a new needle and syringe each time you inject your medicine.

Injection routeYou will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.

Do not use the medicine if it looks cloudy or has particles in it.

Give this medicine within 20 minutes before or after your child eats a meal or snack. Never let your child skip a meal once he has received this medicine.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Injection routeIf you store this medicine at home, keep it in the refrigerator. Do not freeze. Protect from direct heat and light. Use a vial within 30 days after opening.

Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

This medicine is not right for everyone. Your child should not receive it if he had an allergic reaction to mecasermin.

Tell your doctor if your child is pregnant or breastfeeding, or if he or she has kidney disease, liver disease, cancer, diabetes, or a history of scoliosis (curved spine).

This medicine may cause the following problems:Low blood sugarIntracranial hypertension (increased pressure inside the head)Enlarged tonsilsIncreased risk of dislocated hip boneIncreased risk of cancer

This medicine may make your child feel dizzy or faint. Your child should not drive or do anything else that may be dangerous within 2 to 3 hours after receiving the medicine, especially at the start of treatment.

Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion

Swollen tonsils, snoring, trouble breathing or swallowing

Some medicines can affect how mecasermin works. Tell your doctor about all other medicines your child is using, including insulin or other diabetes medicines.

This medicine may cause the following problems:Low blood sugarIntracranial hypertension (increased pressure inside the head)Enlarged tonsilsIncreased risk of dislocated hip bone

This medicine may make your child feel dizzy or faint. Your child should not drive or do anything else that may be dangerous within 2 to 3 hours after receiving the medicine, especially at the start of treatment.

Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Limping, hip or knee pain
• Swollen tonsils, snoring, trouble breathing or swallowing
• Severe headache, vision problems, nausea, vomiting
• Dizziness, drowsiness, trouble concentrating
• Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
• Ear pain or discharge
• Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
• Pain, redness, bruising, or skin changes where the shot was given