Glipizide-Metformin Hcl

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Glipizide-Metformin Hcl

Drug Info for glipizide-metformin hcl

Glipizide is used along with diet and exercise, and sometimes with other medications, to treat type 2 diabetes (condition in which the body does not use insulin normally and, therefore, cannot control the amount of sugar in the blood). Glipizide is in a class of medications called sulfonylureas. Glipizide lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally. Glipizide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated). Over time, people who have diabetes and high blood sugar can develop serious or life-threatening complications, including heart disease, stroke, kidney problems, nerve damage, and eye problems. Taking medication(s), making lifestyle changes (e.g., diet, exercise, quitting smoking), and regularly checking your blood sugar may help to manage your diabetes and improve your health. This therapy may also decrease your chances of having a heart attack, stroke, or other diabetes-related complications such as kidney failure, nerve damage (numb, cold legs or feet; decreased sexual ability in men and women), eye problems, including changes or loss of vision, or gum disease. Your doctor and other healthcare providers will talk to you about the best way to manage your diabetes.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Oral routeIt is best to take this medicine with food or milk.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to glipizide or metformin, or if you have kidney disease or metabolic acidosis.

Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, heart or blood vessel problems, congestive heart failure, adrenal or pituitary gland problems, or G6PD deficiency.

This medicine may cause the following problems:Lactic acidosis (rare, but serious)Higher risk of heart or blood vessel problemsLow blood sugar

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using it before you have surgery, an X-ray, a CT scan, or other medical tests.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Unusual tiredness or weakness

Some foods and medicines can affect how glipizide/metformin works. Tell your doctor if you are using aspirin, chloramphenicol, cimetidine, fluconazole, isoniazid, miconazole, niacin, phenytoin, probenecid, trimethoprim, vancomycin, blood pressure medicines, an NSAID pain or arthritis medicine, an MAO inhibitor, a sulfa medicine, estrogens, birth control pills, thyroid medicine, warfarin or another blood thinner, a diuretic (water pill), a steroid medicine, or a phenothiazine medicine.

If you are also taking colesevelam, take it at least 4 hours after you take glipizide/metformin.

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using it before you have surgery, an X-ray, a CT scan, or other medical tests.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Confusion, fast heartbeat, increased hunger, shakiness, sweating
  • Unusual tiredness or weakness
  • Blurred vision, changes in vision
  • Trouble breathing, lightheadedness, dizziness
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Stomach pain, nausea, vomiting, muscle pain or cramping
  • Mild nausea, diarrhea, or stomach upset