Dihydroergotamine Mesylate

( Generic Migranal )

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$405.31 With Free Coupon
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$1,219.89 With Free Coupon
Dihydroergotamine Mesylate

Drug Info for dihydroergotamine mesylate

Dihydroergotamine is used to treat migraine headaches (severe, throbbing headaches that sometimes are accompanied by nausea and sensitivity to sound and light) and cluster headaches (severe headaches usually on one side of the head or around one eye). Dihydroergotamine is in a class of medications called ergot alkaloids. It works by tightening blood vessels in the brain and by stopping the release of natural substances in the brain that cause swelling.

Dihydroergotamine Mesylate is used to treat the symptoms of migraine headaches. Dihydroergotamine Mesylate is a generic drug. On average Dihydroergotamine Mesylate is priced at about $3,627 for 8, 1ml glass cont of 4 mg/ml injectable solution. Luckily, you can use our OptionRx savings offer to receive a Dihydroergotamine Mesylate discount of up to 80% off the retail price at participating pharmacies near you.

  • D.H.E. 45
  • By injection

Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin (usually in the middle of the thighs), muscle, or through a needle placed into a vein.

Injection routeA nurse or other health provider will give you this medicine.

Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

Use only when you have a migraine. Do not use this medicine for regular headaches.

Check the liquid in the vial. It should be clear and colorless. Do not use it if it is cloudy, discolored, or has particles in it.

If you get another migraine headache after you have used this medicine, do not use a second dose unless it has been more than 6 hours from the last dose.

Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

If you feel much better after a dose of this medicine, but your headache comes back or gets worse after a while, wait at least 1 hour before using another dose.

Store the medicine at room temperature, away from heat and direct light.

Injection routeUse a new needle and syringe each time you inject your medicine.

Injection routeThrow away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to dihydroergotamine mesylate, if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart or blood vessel disease, high blood pressure, angina, severe infection (including sepsis), or a history of heart attack.

This medicine may cause the following problems: Brain problems, including cerebral ischemiaIncreased risk of stroke, heart attack, or heart rhythm problemsStomach problems, including retroperitoneal fibrosisLung problems, including pleural fibrosisIncreased blood pressure

This medicine may make you dizzy or drowsy. Do not drive or do anything else that may be dangerous until you know how the medicine affects you.

This medicine helps stop migraine headaches. It does not relieve pain or stop other kinds of headaches.

Tell your doctor if you have high blood pressure, high cholesterol, diabetes, a history of stroke, or a family history of heart disease. Tell your doctor if you smoke.

Do not breastfeed during treatment and for 3 days after the last dose.

It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Your headaches may become worse if you use headache medicine for 10 or more days per month. This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

This medicine may make you dizzy or drowsy. Do not drive or do anything else that may be dangerous until you know how the medicine affects you.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

Tell your doctor if you use other medicine to treat migraines, including sumatriptan. You should not use sumatriptan or other ergot medicines within 24 hours of using dihydroergotamine.

Some medicines can affect how this medicine works. Tell your doctor if you are using clotrimazole, fluconazole, fluoxetine, fluvoxamine, nefazodone, propranolol, saquinavir, or zileuton.

Do not use this medicine together with clarithromycin, erythromycin, indinavir, itraconazole, ketoconazole, nelfinavir, ritonavir, or troleandomycin.

  • Fast, pounding, or uneven heartbeat, chest pain, wheezing or trouble breathing
  • Lightheadedness, dizziness, fainting
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change or loss of consciousness, drowsiness, lightheadedness, fainting, fast, slow, or uneven heartbeat, seizures, cold, clammy skin
  • Chest pain that may spread to your arms, jaw, back, or neck, trouble breathing, nausea, unusual sweating
  • Muscle pain or weakness
  • Stomach pain, change in how much or how often you urinate, loss of appetite, lower back pain, nausea, vomiting, weakness
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet
  • Confusion, sudden or severe headache, trouble seeing, speaking, or walking
  • Flushing
  • Diarrhea, stomach pain
  • Headache
Frequently Asked Questions

Dihydroergotamine Mesylate is an ergot medication used to treat the symptoms of migraine headaches, including sensitivity to light or sound.

Mesylate, a generic drug, is available under the brand name Migranal. Consult with your doctor for more information about these drugs and to determine the best treatment for you.

The average Alprazolam price without insurance is priced at about $3,627 for 8, 1ml glass cont of 4 mg/ml injectable solution. Prices vary depending on supply needed and pharmacy location.

Dihydroergotamine Mesylate is a generic drug. Similar brand-name drugs include Migranal. Our free coupon may be used for savings on Dihydroergotamine Mesylate and alternative brand-name drugs for savings of up to 80%.

Dihydroergotamine Mesylate injectable solution is available in 1 mg/ml strength. This medication is also available as a nasal spray. Follow your doctor's instructions for dosage and use of this medication.

There is not a Dihydroergotamine Mesylate manufacturer coupon or patient assistance program currently available, but you can save on your prescription cost by using our free Dihydroergotamine Mesylate coupon card. Our coupon card is easy to use, and customers usually find they save the most on medications when using our coupon.