Colesevelam Hcl

( Generic Welchol )
Drug Info

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Colesevelam Hcl

Drug Info for colesevelam hcl

Colesevelam is used in adults along with diet, weight loss, and exercise to reduce the amount of cholesterol and certain fatty substances in the blood alone or in combination with other cholesterol-lowering medications known as HMG-CoA reductase inhibitors (statins). Colesevelam is also used alone or in combination with HMG-CoA reductase inhibitors in certain boys and in girls, ages 10 to 17, with familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally) to decrease the amount of cholesterol and other fatty substances in the blood. Colesevelam is also used along with diet and exercise to control blood sugar levels in adults with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood). Colesevelam is in a class of medications called bile acid sequestrants. It works by binding bile acids in your intestines to form a product that is removed from the body. Bile acids are made when cholesterol is broken down in your body. Removing these bile acids helps to lower your blood cholesterol. Accumulation of cholesterol and fats along the walls of your arteries (a process known as atherosclerosis) decreases blood flow and, therefore, the oxygen supply to your heart, brain, and other parts of your body. Lowering your blood level of cholesterol and fats may help prevent heart disease, angina (chest pain), strokes, and heart attacks.

  • Welchol
  • Tablet
  • Liquid
  • Tablet
  • By mouth

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Your doctor will tell you how much medicine to use. Do not use more than directed.

Carefully follow your doctor's instructions about diet to lower your cholesterol and blood sugar levels.

Take this medicine with a meal and liquid.

Oral liquid: Mix the powder with one cup (8 ounces) of water, fruit juice, or a diet soft drink. Stir well and drink right away.

Tablet: Swallow whole. Do not crush, break, or chew it. If you cannot swallow the tablet, use the oral liquid form of this medicine.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to colesevelam, or if you have a history of bowel blockage, severe hypertriglyceridemia (high fat levels in the blood), or pancreatitis (swelling of the pancreas) caused by hypertriglyceridemia.

Tell your doctor if you are pregnant or breastfeeding, or if you have trouble swallowing, digestion problems (including ongoing problems with constipation), phenylketonuria (PKU), or a history of vitamin A, D, E, or K deficiency. Tell your doctor if you had stomach or bowel surgery.

This medicine may cause the following problems:Pancreatitis (swelling of the pancreas)Stomach or bowel blockageHypertriglyceridemia (high fat levels in the blood), which may cause serious heart problems

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments. Your doctor may check your triglycerides or fatty acids in the blood before using this medicine.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Trouble swallowing

Weakness, confusion, drowsiness, increased hunger, fast heartbeat, or shakiness

Some medicines can affect how colesevelam works. Tell your doctor if you are using any of the following:Cyclosporine, glimepiride, glipizide, glyburide, levothyroxine, olmesartan, phenytoinBirth control pills containing ethinyl estradiol and norethindroneVitamin supplementsTake these medicines at least 4 hours before you use colesevelam.

Tell your doctor if you are also using aspirin, atenolol, cephalexin, ciprofloxacin, digoxin, enalapril, fenofibrate, lovastatin, metformin, metoprolol, pioglitazone, rosiglitazone, quinidine, repaglinide, sitagliptin, valproic acid, verapamil, or warfarin.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Trouble swallowing
  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches
  • Headache, dizziness, lightheadedness, blurred vision
  • Sudden and severe stomach pain, nausea, vomiting, severe constipation, dark urine, yellow skin or eyes
  • Weakness, confusion, drowsiness, increased hunger, fast heartbeat, shakiness
  • Loss of strength
  • Runny or stuffy nose
  • Muscle or joint pain
  • Runny or stuffy nose